SebDuo
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Important Safety Information

Drug Interactions
•    Inform your healthcare provider of all medications you are taking to avoid potential interactions.
Storage Requirements
•    Store at room temperature.
•    Keep out of reach of children.
Beyond Use Date
•    The medication is best used within three months of the date it was made.
•    Do not use or keep outdated medication.
Adverse Effects
Possible side effects may include:
•    Burning sensation
•    Rash
•    Redness
•    Irritation following application
Discontinue use if side effects become bothersome.
With daily, prolonged use, you may experience:
•    Acne-like lesions
•    Appearance of small blood vessels
•    Thinning of the skin
These effects will gradually reverse upon stopping the medication.
Important Precautions:
•    Avoid contact with eyes. If repeated exposure occurs, there may be a risk of cataracts and glaucoma.
•    Always follow your provider’s specific instructions regarding shampoo frequency.
Seek medical attention if any side effects persist after discontinuation.
Usage Instructions
•    SebDuo is a concentrate and should always be used with your regular shampoo, not alone.
•    The standard dose is two pumps of SebDuo per 5ml (1 tsp) of shampoo.
•    Do not apply to broken or bleeding skin.
Contraindications
•    Do not use if you have known allergies to any ingredients in this medication or if you are experiencing certain medical conditions as advised by your healthcare provider. Always consult your provider for more specific contraindications.

SebDuo

A maintenance therapy concentrate for seborrheic dermatitis, designed to mix with YOUR shampoo. Features two FDA-approved ingredients for effective relief from itching, flaking, and redness.

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Formula Highlights
  • Unmatched Convenience - No need to switch shampoos; patients can maintain their favorite brand.
  • Proven Efficacy - Clinically proven ingredients to combat both the symptoms and root causes of seborrheic dermatitis
Active Ingredients

(approximate concentrations after dilution)

  • Ketoconazole (2.3%) – Fights fungal infections that exacerbate dandruff and itching.
  • Triamcinolone Acetonide (0.1%) – Reduces inflammation and soothes the scalp
Shipping Restrictions

NuCara Pharmacies are licensed to dispense to all states excluding Alaska. Please contact MedCara Pharmaceuticals for additional information regarding shipping and state licensing.

How it works
How it works
Step 1 - Mix
Step 1 - Mix

Short Hair or Scalp only:  Mix two pumps of SebDuo with 1 teaspoonful (5 ml) of your shampoo.


Long hair: For hair longer than shoulder length, it's recommended to mix 4 pumps of SebDuo with 2 teaspoonfuls (10 mL) of your shampoo.

Step 2 - Lather
Step 2 - Lather

Lather mixture into hair  and scalp and let sit for 5 minutes for optimal results.

Step 3 - Rinse
Step 3 - Rinse

If product gets into eyes, rinse thoroughly with water.

Transform Your Favorite Shampoo Into a Seborrheic Dermatitis Treatment

SebDuo™ bridges a significant gap in seborrheic dermatitis treatment. With its combination of antifungal and anti-inflammatory agents, it offers unparalleled convenience and efficacy* for patients who seek better results without sacrificing their shampoo preferences.

 

*Based on publications investigating FDA approved products; ketoconazole and triamcinolone acetonide. 

Frequently Asked Questions
Can I apply SebDuo mixed with my shampoo directly to my scalp without first mixing it with my shampoo?

No, it is specifically designed to be COMBINED with your current shampoo. SebDuo should never be applied to the scalp solely by itself.

How will SebDuo affect the performance of my shampoo?

Most people notice that SebDuo makes the shampoo feel smoother resulting in the hair feeling smoother after application. SebDuo has little effect on the foaming or performance from internal testing.

Why did my healthcare provider prescribe SebDuo instead of something that my insurance covers?

SebDuo is most commonly prescribed for seborrheic dermatitis (dandruff).  For people with a significant amount of dandruff, ketoconazole (antifungal medication) plus a topical corticosteroid (I.e., triamcinolone) is the recommended treatment.  However, these two medications are only commercially available as two separate products from your retail pharmacy. Additionally, corticosteroid is available as a leave-in product which cannot be easily applied to the entire scalp and leaves an oily feel. Sebduo provides both ketoconazole and triamcinolone in one convenient concentrate that can be mixed with any shampoo.

Why Can’t SebDuo be sent to my local pharmacy?

SebDuo is a proprietary compounded medication and exclusively available by prescription only from NuCara Pharmacy.

What are the two active ingredients in SebDuo and how do they work?

Ketoconazole and triamcinolone. Ketoconazole has many uses in shampoo form.  The most common is for seborrheic dermatitis (dandruff). Ketoconazole reduces the yeast which is a major cause of this condition and is FDA approved for seborrheic dermatitis. Triamcinolone is a mid-potent topical steroid which is used for many types of inflammatory skin disorders including seborrheic dermatitis.  It is known to be fast acting for the management of itching and flaking of seborrheic dermatitis.

Will my prescription insurance pay for SebDuo?

Since SebDuo is a compounded medication that is custom made, most insurance companies do not cover it. In many cases, prescriptions for SebDuo are eligible for payment using a Flex Spending Account or a Health Savings Account. The patient may also choose to self-submit a claim. If you would like to file an insurance claim, please contact your insurance company for further instructions.

Can I use a conditioner after using SebDuo with my regular shampoo?

Yes. You can continue your hair care routine as usual.

Should I continue using the medication until the bottle is empty?

Most conditions treated by SebDuo are chronic. Healthcare providers typically recommend more frequent use initially until symptoms are controlled, then as needed for maintenance.  A common maintenance dose is twice a month, with more frequent use during acute flares.

How do I know when to decrease the frequency of use to a maintenance dose?

When your symptoms are absent or very well controlled you can use it less often.  Always follow your healthcare provider's instructions and be sure to schedule a follow up if you are not getting the desired results.

Sometimes I shampoo only my scalp and not my hair. Can I do that with SebDuo?

Yes. SebDuo is commonly prescribed for scalp conditions rather than hair conditions. You can use SebDuo alongside your regular shampoo—just add it in. It’s that simple.

I am using a dandruff shampoo that I like but it is not strong enough. Can I combine SebDuo with a dandruff shampoo instead of a non-dandruff shampoo?

Yes. SebDuo can be combined with any dandruff or non-dandruff shampoo.

How do I store the medication? Can I keep it in the shower?

Yes, you can store SebDuo in the shower.  Ideal storage for SebDuo is in a location where it's not constantly exposed to heat.

How do I order SebDuo?

Sebduo requires a prescription.  Dermatologists are typically the most familiar provider with treating scalp conditions. If your healthcare provider is unfamiliar with SebDuo, they can access the provider portal found on the website to learn more. Your prescription will be sent to a NuCara Pharmacy that is properly licensed to mail to your state. Additionally, SebDuo may be prescribed via telemedicine. We recommend contacting SkyMD.com. Please note that we cannot guarantee the provider will prescribe SebDuo, as that decision is up to their clinical judgment.

How long does it take to work and how do I know when to stop treating?

Typically, patients will require 1 to 3 weeks of treatment. The duration of therapy may be longer depending on the severity and area impacted by the condition. A follow-up appointment with your prescriber is beneficial to determine when to discontinue use.

How do I get refills?

Call the pharmacy’s toll-free number found on your prescription label. If you have no refills remaining, the pharmacy will request a new prescription from the clinic. Alternatively, call NuCara Pharmacy and request a refill and we will send a request to your healthcare provider.

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Important Safety Information

Drug Interactions
•    Inform your healthcare provider of all medications you are taking to avoid potential interactions.
Storage Requirements
•    Store at room temperature.
•    Keep out of reach of children.
Beyond Use Date
•    The medication is best used within three months of the date it was made.
•    Do not use or keep outdated medication.
Adverse Effects
Possible side effects may include:
•    Burning sensation
•    Rash
•    Redness
•    Irritation following application
Discontinue use if side effects become bothersome.
With daily, prolonged use, you may experience:
•    Acne-like lesions
•    Appearance of small blood vessels
•    Thinning of the skin
These effects will gradually reverse upon stopping the medication.
Important Precautions:
•    Avoid contact with eyes. If repeated exposure occurs, there may be a risk of cataracts and glaucoma.
•    Always follow your provider’s specific instructions regarding shampoo frequency.
Seek medical attention if any side effects persist after discontinuation.
Usage Instructions
•    SebDuo is a concentrate and should always be used with your regular shampoo, not alone.
•    The standard dose is two pumps of SebDuo per 5ml (1 tsp) of shampoo.
•    Do not apply to broken or bleeding skin.
Contraindications
•    Do not use if you have known allergies to any ingredients in this medication or if you are experiencing certain medical conditions as advised by your healthcare provider. Always consult your provider for more specific contraindications.

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